Program overview
Context
Indication: Lung Cancer
Mechanism: Unknown
Modality: Unknown
Sponsor: Canadian Cancer Trials Group
Registry Stop Signal
Pembrolizumab
Pembrolizumab is flagged as registry stop signal because public records show a registry stop signal, timeline staleness, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 5/5
Timeline: 3/5
Recruitment burden: 3/5
Results availability: 0/5
Program risk: 5/5
Evidence
Public links
https://clinicaltrials.gov/study/NCT04093167 | https://clinicaltrials.gov/study/NCT03835819 | https://clinicaltrials.gov/study/NCT04924101 | https://clinicaltrials.gov/study/NCT04118036 | https://clinicaltrials.gov/study/NCT04995016 | https://clinicaltrials.gov/study/NCT05419817 | https://clinicaltrials.gov/study/NCT01905657 | https://clinicaltrials.gov/study/NCT03402880 | https://clinicaltrials.gov/study/NCT06364917 | https://clinicaltrials.gov/study/NCT03752333 | https://clinicaltrials.gov/study/NCT04575961 | https://clinicaltrials.gov/study/NCT04754815 | https://clinicaltrials.gov/study/NCT05467670 | https://clinicaltrials.gov/study/NCT04190056 | https://clinicaltrials.gov/study/NCT06822543 | https://clinicaltrials.gov/study/NCT06305767
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCT04093167 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | large_enrollment_target_signal | rare_population_signal | strict_eligibility_signal |
| NCT03835819 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT04924101 | Low Signal (COMPLETED) | None | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT04118036 | Registry Stop Signal (WITHDRAWN) | None | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT04995016 | Unknown Status Signal (UNKNOWN) | stale_update_signal | primary_completion_date_past_signal | completion_date_past_signal | Low Signal | strict_eligibility_signal |
| NCT05419817 | Registry Stop Signal (WITHDRAWN) | stale_update_signal | Low Signal | strict_eligibility_signal |
| NCT01905657 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | large_enrollment_target_signal | few_sites_large_trial_signal |
| NCT03402880 | Registry Stop Signal (WITHDRAWN) | None | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT06364917 | Low Signal (RECRUITING) | None | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT03752333 | Low Signal (COMPLETED) | None | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT04575961 | Low Signal (ACTIVE_NOT_RECRUITING) | stale_update_signal | long_recruitment_duration_signal | Low Signal | strict_eligibility_signal |
| NCT04754815 | Registry Stop Signal (WITHDRAWN) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT05467670 | Low Signal (ACTIVE_NOT_RECRUITING) | long_recruitment_duration_signal | Low Signal | strict_eligibility_signal |
| NCT04190056 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | strict_eligibility_signal |
| NCT06822543 | Low Signal (RECRUITING) | None | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT06305767 | Low Signal (ACTIVE_NOT_RECRUITING) | long_recruitment_duration_signal | Low Signal | large_enrollment_target_signal |