Program overview
Context
Indication: Waldenstrom Macroglobulinemia
Mechanism: Unknown
Modality: Unknown
Sponsor: Shayna Sarosiek, MD
Registry Stop Signal
Loncastuximab Tesirine
Loncastuximab Tesirine is flagged as registry stop signal because public records show a registry stop signal, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 5/5
Timeline: 1/5
Recruitment burden: 3/5
Results availability: 0/5
Program risk: 4/5
Evidence
Public links
https://clinicaltrials.gov/study/NCT05190705 | https://clinicaltrials.gov/study/NCT06788964 | https://clinicaltrials.gov/study/NCT05144009 | https://clinicaltrials.gov/study/NCT04998669 | https://clinicaltrials.gov/study/NCT05453396 | https://clinicaltrials.gov/study/NCT03684694
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCT05190705 | Low Signal (ACTIVE_NOT_RECRUITING) | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT06788964 | Low Signal (RECRUITING) | None | Low Signal | strict_eligibility_signal | complex_intervention_signal |
| NCT05144009 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT04998669 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT05453396 | Registry Stop Signal (TERMINATED) | None | Low Signal | rare_population_signal | strict_eligibility_signal | complex_intervention_signal |
| NCT03684694 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |