Program overview
Context
Indication: Recurrent Melanoma
Mechanism: Unknown
Modality: Unknown
Sponsor: National Cancer Institute (NCI)
Registry Stop Signal
cyclophosphamide
cyclophosphamide is flagged as registry stop signal because public records show a registry stop signal, timeline staleness, public results not found after completion, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 5/5
Timeline: 2/5
Recruitment burden: 2/5
Results availability: 3/5
Program risk: 5/5
Evidence
Public links
https://clinicaltrials.gov/study/NCT00303836 | https://clinicaltrials.gov/study/NCT02414945 | https://clinicaltrials.gov/study/NCT00958854 | https://clinicaltrials.gov/study/NCT05600686
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCT00303836 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT02414945 | Low Signal (COMPLETED) | stale_update_signal | Completed No Results Found Signal | rare_population_signal |
| NCT00958854 | Unknown Status Signal (UNKNOWN) | stale_update_signal | primary_completion_date_past_signal | Low Signal | strict_eligibility_signal |
| NCT05600686 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |