Program overview
Context
Indication: Metastatic Melanoma
Mechanism: Unknown
Modality: Unknown
Sponsor: Hoffmann-La Roche
Registry Stop Signal
Cobimetinib
Cobimetinib is flagged as registry stop signal because public records show a registry stop signal, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 5/5
Timeline: 1/5
Recruitment burden: 2/5
Results availability: 0/5
Program risk: 4/5
Evidence
Public links
https://clinicaltrials.gov/study/NCT03625141 | https://clinicaltrials.gov/study/NCT02322814 | https://clinicaltrials.gov/study/NCT02230306
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCT03625141 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | rare_population_signal |
| NCT02322814 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT02230306 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | rare_population_signal |