Program overview
Context
Indication: Metastatic Colorectal Cancer
Mechanism: Unknown
Modality: Unknown
Sponsor: The Christie NHS Foundation Trust
Registry Stop Signal
Cetuximab
Cetuximab is flagged as registry stop signal because public records show a registry stop signal, timeline staleness, public results not found after completion, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 5/5
Timeline: 2/5
Recruitment burden: 2/5
Results availability: 3/5
Program risk: 5/5
Evidence
Public links
https://clinicaltrials.gov/study/NCT01225744 | https://clinicaltrials.gov/study/NCT04554836 | https://clinicaltrials.gov/study/NCT05312398 | https://clinicaltrials.gov/study/NCT00971932 | https://clinicaltrials.gov/study/NCT01427205 | https://clinicaltrials.gov/study/NCT01190462
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCT01225744 | Low Signal (COMPLETED) | stale_update_signal | Completed No Results Found Signal | rare_population_signal |
| NCT04554836 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT05312398 | Low Signal (ACTIVE_NOT_RECRUITING) | stale_update_signal | long_recruitment_duration_signal | Low Signal | large_enrollment_target_signal | strict_eligibility_signal |
| NCT00971932 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | strict_eligibility_signal |
| NCT01427205 | Registry Stop Signal (WITHDRAWN) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT01190462 | Unknown Status Signal (UNKNOWN) | stale_update_signal | primary_completion_date_past_signal | Low Signal | rare_population_signal |