Program overview
Context
Indication: Adult Grade III Lymphomatoid Granulomatosis
Mechanism: Unknown
Modality: Unknown
Sponsor: Northwestern University
Registry Stop Signal
brentuximab vedotin
brentuximab vedotin is flagged as registry stop signal because public records show a registry stop signal, timeline staleness, public results not found after completion, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 5/5
Timeline: 2/5
Recruitment burden: 3/5
Results availability: 3/5
Program risk: 5/5
Evidence
Public links
https://clinicaltrials.gov/study/NCT01805037 | https://clinicaltrials.gov/study/NCT02988843 | https://clinicaltrials.gov/study/NCT02588651 | https://clinicaltrials.gov/study/NCT03007030 | https://clinicaltrials.gov/study/NCT02388490 | https://clinicaltrials.gov/study/NCT04745949 | https://clinicaltrials.gov/study/NCT04561206 | https://clinicaltrials.gov/study/NCT03409432 | https://clinicaltrials.gov/study/NCT02744612 | https://clinicaltrials.gov/study/NCT03233347 | https://clinicaltrials.gov/study/NCT06377566 | https://clinicaltrials.gov/study/NCT04795869 | https://clinicaltrials.gov/study/NCT01534078 | https://clinicaltrials.gov/study/NCT01771107 | https://clinicaltrials.gov/study/NCT05039073 | https://clinicaltrials.gov/study/NCT05673785 | https://clinicaltrials.gov/study/NCT01492088 | https://clinicaltrials.gov/study/NCT03113500 | https://clinicaltrials.gov/study/NCT01393717 | https://clinicaltrials.gov/study/NCT01780662
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCT01805037 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | strict_eligibility_signal |
| NCT02988843 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT02588651 | Low Signal (COMPLETED) | None | Low Signal | strict_eligibility_signal |
| NCT03007030 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | strict_eligibility_signal |
| NCT02388490 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | None |
| NCT04745949 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT04561206 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT03409432 | Low Signal (COMPLETED) | None | Completed No Results Found Signal | strict_eligibility_signal |
| NCT02744612 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT03233347 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT06377566 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | None |
| NCT04795869 | Registry Stop Signal (WITHDRAWN) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT01534078 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT01771107 | Low Signal (COMPLETED) | None | Low Signal | strict_eligibility_signal |
| NCT05039073 | Low Signal (RECRUITING) | long_recruitment_duration_signal | Low Signal | strict_eligibility_signal |
| NCT05673785 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT01492088 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT03113500 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal | complex_intervention_signal |
| NCT01393717 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |
| NCT01780662 | Low Signal (COMPLETED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal |