Program overview
Context
Indication: AL Amyloidosis
Mechanism: Unknown
Modality: Unknown
Sponsor: Stichting European Myeloma Network
Registry Stop Signal
Belantamab mafodotin
Belantamab mafodotin is flagged as registry stop signal because public records show a registry stop signal, timeline staleness, public results not found after completion, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 5/5
Timeline: 2/5
Recruitment burden: 4/5
Results availability: 3/5
Program risk: 5/5
Evidence
Public links
https://clinicaltrials.gov/study/NCT04617925 | https://clinicaltrials.gov/study/NCT07217184 | https://clinicaltrials.gov/study/NCT04126200 | https://clinicaltrials.gov/study/NCT07150091 | https://clinicaltrials.gov/study/NCT06655818 | https://clinicaltrials.gov/study/NCT07150104 | https://clinicaltrials.gov/study/NCT05064358
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCT04617925 | Low Signal (COMPLETED) | None | Completed No Results Found Signal | rare_population_signal | strict_eligibility_signal |
| NCT07217184 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal | complex_intervention_signal |
| NCT04126200 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | large_enrollment_target_signal | rare_population_signal | strict_eligibility_signal | complex_intervention_signal |
| NCT07150091 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal | complex_intervention_signal |
| NCT06655818 | Registry Stop Signal (TERMINATED) | stale_update_signal | Low Signal | rare_population_signal | strict_eligibility_signal | complex_intervention_signal |
| NCT07150104 | Low Signal (ACTIVE_NOT_RECRUITING) | primary_completion_date_past_signal | long_recruitment_duration_signal | Low Signal | rare_population_signal | strict_eligibility_signal | complex_intervention_signal |
| NCT05064358 | Low Signal (COMPLETED) | None | Low Signal | strict_eligibility_signal |