Manual Review Required

RET fusion

ovarian cancer · Therapy Not Normalized

RET fusion is flagged as manual review required because public trials show inclusion required evidence in 27 contexts. FDA CDx context should be reviewed manually.

Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 23

Treatment-assignment count: 0

Stratification count: 0

Threshold snippets

Fragmentation view

Threshold count: 2

Common snippets: MSI-H | MSI-H

Threshold label: Moderate

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Not Found

CDx maturity score: 1/5

Confidence: Low

Patent-density signal

Diagnostic appendix

Signal count: 0

Recent signals: 0

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT00825201 | https://clinicaltrials.gov/study/NCT00388037 | https://clinicaltrials.gov/study/NCT00551070 | https://clinicaltrials.gov/study/NCT05591560 | https://clinicaltrials.gov/study/NCT01716715 | https://clinicaltrials.gov/study/NCT00301756 | https://clinicaltrials.gov/study/NCT00058552 | https://clinicaltrials.gov/study/NCT04614051 | https://clinicaltrials.gov/study/NCT00951496 | https://clinicaltrials.gov/study/NCT05199272 | https://clinicaltrials.gov/study/NCT05041257 | https://clinicaltrials.gov/study/NCT01609556 | https://clinicaltrials.gov/study/NCT05622890 | https://clinicaltrials.gov/study/NCT02111941 | https://clinicaltrials.gov/study/NCT03552471 | https://clinicaltrials.gov/study/NCT07617753 | https://clinicaltrials.gov/study/NCT06390995 | https://clinicaltrials.gov/study/NCT04274426 | https://clinicaltrials.gov/study/NCT07604766 | https://clinicaltrials.gov/study/NCT04209855 | https://clinicaltrials.gov/study/NCT03585764 | https://clinicaltrials.gov/study/NCT06639074 | https://clinicaltrials.gov/study/NCT03180307 | https://clinicaltrials.gov/study/NCT06619236 | https://clinicaltrials.gov/study/NCT02317705 | https://clinicaltrials.gov/study/NCT04296890 | https://clinicaltrials.gov/study/NCT06365853