Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 23
Treatment-assignment count: 0
Stratification count: 5
Manual Review Required
PD-L1 expression
solid tumor basket · Small Molecule Inhibitor
PD-L1 expression is flagged as manual review required because public trials show inclusion required evidence in 56 contexts. FDA CDx context should be reviewed manually. Threshold text varies across public records.
Threshold snippets
Fragmentation view
Threshold count: 29
Common snippets: PD-L1 CPS ≥1 | HER2 IHC 3+ | HER2 IHC 3+
Threshold label: Fragmented
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 1
Recent signals: 1
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT07071103 | https://clinicaltrials.gov/study/NCT03803774 | https://clinicaltrials.gov/study/NCT07662720 | https://clinicaltrials.gov/study/NCT04601857 | https://clinicaltrials.gov/study/NCT04729725 | https://clinicaltrials.gov/study/NCT07404332 | https://clinicaltrials.gov/study/NCT05507541 | https://clinicaltrials.gov/study/NCT06340568 | https://clinicaltrials.gov/study/NCT07142200 | https://clinicaltrials.gov/study/NCT05821751 | https://clinicaltrials.gov/study/NCT05445648 | https://clinicaltrials.gov/study/NCT02935361 | https://clinicaltrials.gov/study/NCT03082534 | https://clinicaltrials.gov/study/NCT03495323 | https://clinicaltrials.gov/study/NCT04284787 | https://clinicaltrials.gov/study/NCT07238569 | https://clinicaltrials.gov/study/NCT04550624 | https://clinicaltrials.gov/study/NCT03884998 | https://clinicaltrials.gov/study/NCT03971214 | https://clinicaltrials.gov/study/NCT04963153 | https://clinicaltrials.gov/study/NCT04800978 | https://clinicaltrials.gov/study/NCT05659251 | https://clinicaltrials.gov/study/NCT05425602 | https://clinicaltrials.gov/study/NCT07497919 | https://clinicaltrials.gov/study/NCT05354323 | https://clinicaltrials.gov/study/NCT06614140 | https://clinicaltrials.gov/study/NCT04282109 | https://clinicaltrials.gov/study/NCT06439836 | https://clinicaltrials.gov/study/NCT06528210 | https://clinicaltrials.gov/study/NCT04681469 | https://clinicaltrials.gov/study/NCT05505825 | https://clinicaltrials.gov/study/NCT07692932 | https://clinicaltrials.gov/study/NCT06576973 | https://clinicaltrials.gov/study/NCT05440864 | https://clinicaltrials.gov/study/NCT03827044 | https://clinicaltrials.gov/study/NCT04512534 | https://clinicaltrials.gov/study/NCT03601455 | https://clinicaltrials.gov/study/NCT06151743 | https://clinicaltrials.gov/study/NCT04019964 | https://clinicaltrials.gov/study/NCT03544723 | https://clinicaltrials.gov/study/NCT03697304 | https://clinicaltrials.gov/study/NCT03816345 | https://clinicaltrials.gov/study/NCT03694834 | https://clinicaltrials.gov/study/NCT05860335 | https://clinicaltrials.gov/study/NCT07319429 | https://clinicaltrials.gov/study/NCT03607890 | https://clinicaltrials.gov/study/NCT04389151 | https://clinicaltrials.gov/study/NCT07270666 | https://clinicaltrials.gov/study/NCT07243626 | https://clinicaltrials.gov/study/NCT05879822 | https://clinicaltrials.gov/study/NCT05550558 | https://clinicaltrials.gov/study/NCT06914297 | https://clinicaltrials.gov/study/NCT03026140 | https://clinicaltrials.gov/study/NCT06270706 | https://clinicaltrials.gov/study/NCT04150900 | https://clinicaltrials.gov/study/NCT04576091