Manual Review Required

PD-L1 expression

solid tumor basket · Immune Checkpoint Inhibitor

PD-L1 expression is flagged as manual review required because public trials show inclusion required evidence in 83 contexts. FDA CDx context exists.

Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 48

Treatment-assignment count: 2

Stratification count: 0

Threshold snippets

Fragmentation view

Threshold count: 35

Common snippets: KRAS G12C | KRAS G12C | dMMR

Threshold label: Moderate

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Exists

CDx maturity score: 5/5

Confidence: Low

Patent-density signal

Diagnostic appendix

Signal count: 1

Recent signals: 1

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT05934331 | https://clinicaltrials.gov/study/NCT06288191 | https://clinicaltrials.gov/study/NCT03402880 | https://clinicaltrials.gov/study/NCT03364049 | https://clinicaltrials.gov/study/NCT03752333 | https://clinicaltrials.gov/study/NCT03307616 | https://clinicaltrials.gov/study/NCT03792724 | https://clinicaltrials.gov/study/NCT03502733 | https://clinicaltrials.gov/study/NCT02587962 | https://clinicaltrials.gov/study/NCT05647265 | https://clinicaltrials.gov/study/NCT03371381 | https://clinicaltrials.gov/study/NCT03881111 | https://clinicaltrials.gov/study/NCT04555837 | https://clinicaltrials.gov/study/NCT04118166 | https://clinicaltrials.gov/study/NCT02973997 | https://clinicaltrials.gov/study/NCT03267498 | https://clinicaltrials.gov/study/NCT03416335 | https://clinicaltrials.gov/study/NCT05067283 | https://clinicaltrials.gov/study/NCT05727410 | https://clinicaltrials.gov/study/NCT07213557 | https://clinicaltrials.gov/study/NCT05323656 | https://clinicaltrials.gov/study/NCT03065764 | https://clinicaltrials.gov/study/NCT04936841 | https://clinicaltrials.gov/study/NCT06640283 | https://clinicaltrials.gov/study/NCT04326257 | https://clinicaltrials.gov/study/NCT03172754 | https://clinicaltrials.gov/study/NCT03680521 | https://clinicaltrials.gov/study/NCT03898180 | https://clinicaltrials.gov/study/NCT06823479 | https://clinicaltrials.gov/study/NCT03558750 | https://clinicaltrials.gov/study/NCT07196384 | https://clinicaltrials.gov/study/NCT04862455 | https://clinicaltrials.gov/study/NCT04603248 | https://clinicaltrials.gov/study/NCT03367741 | https://clinicaltrials.gov/study/NCT02648997 | https://clinicaltrials.gov/study/NCT05346484 | https://clinicaltrials.gov/study/NCT03385226 | https://clinicaltrials.gov/study/NCT06919666 | https://clinicaltrials.gov/study/NCT02775812 | https://clinicaltrials.gov/study/NCT04541277 | https://clinicaltrials.gov/study/NCT05063552 | https://clinicaltrials.gov/study/NCT03506360 | https://clinicaltrials.gov/study/NCT03873402 | https://clinicaltrials.gov/study/NCT05662527 | https://clinicaltrials.gov/study/NCT02437370 | https://clinicaltrials.gov/study/NCT07469774 | https://clinicaltrials.gov/study/NCT03990961 | https://clinicaltrials.gov/study/NCT04969861 | https://clinicaltrials.gov/study/NCT03530397 | https://clinicaltrials.gov/study/NCT01668784 | https://clinicaltrials.gov/study/NCT02550249 | https://clinicaltrials.gov/study/NCT02252042 | https://clinicaltrials.gov/study/NCT03463460 | https://clinicaltrials.gov/study/NCT06395090 | https://clinicaltrials.gov/study/NCT03126110 | https://clinicaltrials.gov/study/NCT04041310 | https://clinicaltrials.gov/study/NCT04774419 | https://clinicaltrials.gov/study/NCT04412408 | https://clinicaltrials.gov/study/NCT04082572 | https://clinicaltrials.gov/study/NCT03832569 | https://clinicaltrials.gov/study/NCT04009967 | https://clinicaltrials.gov/study/NCT04800627 | https://clinicaltrials.gov/study/NCT03241745 | https://clinicaltrials.gov/study/NCT04262089 | https://clinicaltrials.gov/study/NCT04214067 | https://clinicaltrials.gov/study/NCT05173987 | https://clinicaltrials.gov/study/NCT02992964 | https://clinicaltrials.gov/study/NCT04500548 | https://clinicaltrials.gov/study/NCT05584670 | https://clinicaltrials.gov/study/NCT03914612 | https://clinicaltrials.gov/study/NCT02359565 | https://clinicaltrials.gov/study/NCT05795244 | https://clinicaltrials.gov/study/NCT04439214 | https://clinicaltrials.gov/study/NCT03668119 | https://clinicaltrials.gov/study/NCT06356155 | https://clinicaltrials.gov/study/NCT04634877 | https://clinicaltrials.gov/study/NCT04098068 | https://clinicaltrials.gov/study/NCT03958045 | https://clinicaltrials.gov/study/NCT05200988 | https://clinicaltrials.gov/study/NCT03718767 | https://clinicaltrials.gov/study/NCT04131621 | https://clinicaltrials.gov/study/NCT04761198 | https://clinicaltrials.gov/study/NCT05148546