Manual Review Required

PD-L1 expression

NSCLC · Combination Therapy

PD-L1 expression is flagged as manual review required because public trials show inclusion required evidence in 32 contexts. FDA CDx context exists.

Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 24

Treatment-assignment count: 0

Stratification count: 0

Threshold snippets

Fragmentation view

Threshold count: 7

Common snippets: EGFR L858R | EGFR exon 19 deletion | KRAS G12C

Threshold label: Moderate

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Exists

CDx maturity score: 5/5

Confidence: Low

Patent-density signal

Diagnostic appendix

Signal count: 1

Recent signals: 1

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT07115043 | https://clinicaltrials.gov/study/NCT06668103 | https://clinicaltrials.gov/study/NCT03775486 | https://clinicaltrials.gov/study/NCT06334757 | https://clinicaltrials.gov/study/NCT04552613 | https://clinicaltrials.gov/study/NCT05394233 | https://clinicaltrials.gov/study/NCT04459663 | https://clinicaltrials.gov/study/NCT06746870 | https://clinicaltrials.gov/study/NCT04042558 | https://clinicaltrials.gov/study/NCT03164616 | https://clinicaltrials.gov/study/NCT07227025 | https://clinicaltrials.gov/study/NCT06749860 | https://clinicaltrials.gov/study/NCT04940637 | https://clinicaltrials.gov/study/NCT05346952 | https://clinicaltrials.gov/study/NCT03317496 | https://clinicaltrials.gov/study/NCT06974734 | https://clinicaltrials.gov/study/NCT05568212 | https://clinicaltrials.gov/study/NCT05635708 | https://clinicaltrials.gov/study/NCT03896074 | https://clinicaltrials.gov/study/NCT04832854 | https://clinicaltrials.gov/study/NCT06580665 | https://clinicaltrials.gov/study/NCT04167774 | https://clinicaltrials.gov/study/NCT03170960 | https://clinicaltrials.gov/study/NCT05746481 | https://clinicaltrials.gov/study/NCT02888743 | https://clinicaltrials.gov/study/NCT04866017 | https://clinicaltrials.gov/study/NCT04105270 | https://clinicaltrials.gov/study/NCT06982924 | https://clinicaltrials.gov/study/NCT03475953 | https://clinicaltrials.gov/study/NCT03472560 | https://clinicaltrials.gov/study/NCT05800340 | https://clinicaltrials.gov/study/NCT04323436