Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 7
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
MSI-H / dMMR
solid tumor basket · Small Molecule Inhibitor
MSI-H / dMMR is flagged as manual review required because public trials show inclusion required evidence in 16 contexts. FDA CDx context should be reviewed manually.
Threshold snippets
Fragmentation view
Threshold count: 28
Common snippets: dMMR | dMMR | dMMR
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT04800978 | https://clinicaltrials.gov/study/NCT03827044 | https://clinicaltrials.gov/study/NCT04019964 | https://clinicaltrials.gov/study/NCT03816345 | https://clinicaltrials.gov/study/NCT03694834 | https://clinicaltrials.gov/study/NCT07319429 | https://clinicaltrials.gov/study/NCT03607890 | https://clinicaltrials.gov/study/NCT04389151 | https://clinicaltrials.gov/study/NCT07270666 | https://clinicaltrials.gov/study/NCT07243626 | https://clinicaltrials.gov/study/NCT05879822 | https://clinicaltrials.gov/study/NCT05550558 | https://clinicaltrials.gov/study/NCT06914297 | https://clinicaltrials.gov/study/NCT03026140 | https://clinicaltrials.gov/study/NCT04104893 | https://clinicaltrials.gov/study/NCT07690540