Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 13
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
MSI-H / dMMR
solid tumor basket · Monoclonal Antibody
MSI-H / dMMR is flagged as manual review required because public trials show inclusion required evidence in 21 contexts. FDA CDx context should be reviewed manually.
Threshold snippets
Fragmentation view
Threshold count: 41
Common snippets: dMMR | dMMR | MSI-H
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT05631899 | https://clinicaltrials.gov/study/NCT05256225 | https://clinicaltrials.gov/study/NCT03657381 | https://clinicaltrials.gov/study/NCT03736889 | https://clinicaltrials.gov/study/NCT07053332 | https://clinicaltrials.gov/study/NCT03810339 | https://clinicaltrials.gov/study/NCT04068519 | https://clinicaltrials.gov/study/NCT03704246 | https://clinicaltrials.gov/study/NCT02715284 | https://clinicaltrials.gov/study/NCT04636008 | https://clinicaltrials.gov/study/NCT06046274 | https://clinicaltrials.gov/study/NCT04547101 | https://clinicaltrials.gov/study/NCT04411524 | https://clinicaltrials.gov/study/NCT03474640 | https://clinicaltrials.gov/study/NCT05231850 | https://clinicaltrials.gov/study/NCT03803553 | https://clinicaltrials.gov/study/NCT05890742 | https://clinicaltrials.gov/study/NCT06321068 | https://clinicaltrials.gov/study/NCT07369986 | https://clinicaltrials.gov/study/NCT05152212 | https://clinicaltrials.gov/study/NCT05592626