Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 11
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
MSI-H / dMMR
solid tumor basket · Immune Checkpoint Inhibitor
MSI-H / dMMR is flagged as manual review required because public trials show inclusion required evidence in 19 contexts. FDA CDx context exists.
Threshold snippets
Fragmentation view
Threshold count: 33
Common snippets: dMMR | dMMR | dMMR
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Exists
CDx maturity score: 5/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT05732389 | https://clinicaltrials.gov/study/NCT05662527 | https://clinicaltrials.gov/study/NCT06395090 | https://clinicaltrials.gov/study/NCT04041310 | https://clinicaltrials.gov/study/NCT04774419 | https://clinicaltrials.gov/study/NCT04412408 | https://clinicaltrials.gov/study/NCT04082572 | https://clinicaltrials.gov/study/NCT04751370 | https://clinicaltrials.gov/study/NCT04009967 | https://clinicaltrials.gov/study/NCT04800627 | https://clinicaltrials.gov/study/NCT03241745 | https://clinicaltrials.gov/study/NCT04262089 | https://clinicaltrials.gov/study/NCT05419817 | https://clinicaltrials.gov/study/NCT04214067 | https://clinicaltrials.gov/study/NCT05173987 | https://clinicaltrials.gov/study/NCT05584670 | https://clinicaltrials.gov/study/NCT03914612 | https://clinicaltrials.gov/study/NCT05795244 | https://clinicaltrials.gov/study/NCT03718767