Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 6
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
MSI-H / dMMR
solid tumor basket · Combination Therapy
MSI-H / dMMR is flagged as manual review required because public trials show inclusion required evidence in 9 contexts. FDA CDx context should be reviewed manually.
Threshold snippets
Fragmentation view
Threshold count: 17
Common snippets: MSI-H | MSI-H | dMMR
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT07403721 | https://clinicaltrials.gov/study/NCT07108270 | https://clinicaltrials.gov/study/NCT06771154 | https://clinicaltrials.gov/study/NCT06873854 | https://clinicaltrials.gov/study/NCT05005728 | https://clinicaltrials.gov/study/NCT05729646 | https://clinicaltrials.gov/study/NCT06341114 | https://clinicaltrials.gov/study/NCT06279130 | https://clinicaltrials.gov/study/NCT02912559