Role evidence
Usage summary
Strongest role: Stratification
Inclusion-required count: 0
Treatment-assignment count: 0
Stratification count: 1
Manual Review Required
MSI-H / dMMR
NSCLC · Therapy Not Normalized
MSI-H / dMMR is flagged as manual review required because public trials show stratification evidence in 3 contexts. FDA CDx context should be reviewed manually. Threshold text varies across public records.
Threshold snippets
Fragmentation view
Threshold count: 4
Common snippets: PD-L1 TPS ≥ 50% | dMMR | TMB ≥19 mut/Mb
Threshold label: Fragmented
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT06865339 | https://clinicaltrials.gov/study/NCT05770102 | https://clinicaltrials.gov/study/NCT02983578