Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 3
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
MSI-H / dMMR
NSCLC · Small Molecule Inhibitor
MSI-H / dMMR is flagged as manual review required because public trials show inclusion required evidence in 10 contexts. FDA CDx context should be reviewed manually.
Threshold snippets
Fragmentation view
Threshold count: 16
Common snippets: MSI-H | MSI-H | MSI-H
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT04417465 | https://clinicaltrials.gov/study/NCT03236935 | https://clinicaltrials.gov/study/NCT07555210 | https://clinicaltrials.gov/study/NCT07595523 | https://clinicaltrials.gov/study/NCT04401059 | https://clinicaltrials.gov/study/NCT03190174 | https://clinicaltrials.gov/study/NCT04187872 | https://clinicaltrials.gov/study/NCT05086692 | https://clinicaltrials.gov/study/NCT07689812 | https://clinicaltrials.gov/study/NCT03156114