Manual Review Required

MSI-H / dMMR

gastric cancer · Immune Checkpoint Inhibitor

MSI-H / dMMR is flagged as manual review required because public trials show inclusion required evidence in 11 contexts. FDA CDx context exists.

Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 8

Treatment-assignment count: 0

Stratification count: 0

Threshold snippets

Fragmentation view

Threshold count: 16

Common snippets: MSI-h | MSI-h | MSI-h

Threshold label: Moderate

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Exists

CDx maturity score: 5/5

Confidence: Low

Patent-density signal

Diagnostic appendix

Signal count: 0

Recent signals: 0

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT03505320 | https://clinicaltrials.gov/study/NCT05535569 | https://clinicaltrials.gov/study/NCT07223424 | https://clinicaltrials.gov/study/NCT02589496 | https://clinicaltrials.gov/study/NCT03407976 | https://clinicaltrials.gov/study/NCT03894618 | https://clinicaltrials.gov/study/NCT03257163 | https://clinicaltrials.gov/study/NCT07542262 | https://clinicaltrials.gov/study/NCT04006262 | https://clinicaltrials.gov/study/NCT07673887 | https://clinicaltrials.gov/study/NCT06901531