Manual Review Required

MSI-H / dMMR

gastric cancer · Combination Therapy

MSI-H / dMMR is flagged as manual review required because public trials show inclusion required evidence in 15 contexts. FDA CDx context exists.

Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 9

Treatment-assignment count: 0

Stratification count: 0

Threshold snippets

Fragmentation view

Threshold count: 25

Common snippets: dMMR | dMMR | dMMR

Threshold label: Moderate

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Exists

CDx maturity score: 5/5

Confidence: Low

Patent-density signal

Diagnostic appendix

Signal count: 0

Recent signals: 0

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT07658872 | https://clinicaltrials.gov/study/NCT06426654 | https://clinicaltrials.gov/study/NCT05769725 | https://clinicaltrials.gov/study/NCT04603040 | https://clinicaltrials.gov/study/NCT07266025 | https://clinicaltrials.gov/study/NCT05836584 | https://clinicaltrials.gov/study/NCT05177133 | https://clinicaltrials.gov/study/NCT04152889 | https://clinicaltrials.gov/study/NCT06974110 | https://clinicaltrials.gov/study/NCT07692204 | https://clinicaltrials.gov/study/NCT06250036 | https://clinicaltrials.gov/study/NCT05002686 | https://clinicaltrials.gov/study/NCT05713838 | https://clinicaltrials.gov/study/NCT03935893 | https://clinicaltrials.gov/study/NCT04221555