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TreelipBiomarker Patient-Selection Radar
Solid Tumor OncologyMethodology
Manual Review Required

KRAS G12D

NSCLC · Therapy Not Normalized

KRAS G12D is flagged as manual review required because public trials show inclusion required evidence in 28 contexts. FDA CDx context should be reviewed manually.

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Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 23

Treatment-assignment count: 0

Stratification count: 1

Threshold snippets

Fragmentation view

Threshold count: 25

Common snippets: BRAF V600E | EGFR exon 19 deletion | KRAS G12C

Threshold label: Moderate

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Not Found

CDx maturity score: 1/5

Confidence: Low

Patent-density signal

Diagnostic appendix

Signal count: 0

Recent signals: 0

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT02642042 | https://clinicaltrials.gov/study/NCT07291037 | https://clinicaltrials.gov/study/NCT02417701 | https://clinicaltrials.gov/study/NCT04250545 | https://clinicaltrials.gov/study/NCT02607813 | https://clinicaltrials.gov/study/NCT01829217 | https://clinicaltrials.gov/study/NCT00858403 | https://clinicaltrials.gov/study/NCT01124864 | https://clinicaltrials.gov/study/NCT06563999 | https://clinicaltrials.gov/study/NCT00548093 | https://clinicaltrials.gov/study/NCT07542704 | https://clinicaltrials.gov/study/NCT06416410 | https://clinicaltrials.gov/study/NCT05383898 | https://clinicaltrials.gov/study/NCT06403436 | https://clinicaltrials.gov/study/NCT04302025 | https://clinicaltrials.gov/study/NCT05119933 | https://clinicaltrials.gov/study/NCT06300177 | https://clinicaltrials.gov/study/NCT05009329 | https://clinicaltrials.gov/study/NCT05005234 | https://clinicaltrials.gov/study/NCT04165031 | https://clinicaltrials.gov/study/NCT06008288 | https://clinicaltrials.gov/study/NCT06208124 | https://clinicaltrials.gov/study/NCT07286149 | https://clinicaltrials.gov/study/NCT04006301 | https://clinicaltrials.gov/study/NCT05445843 | https://clinicaltrials.gov/study/NCT05397093 | https://clinicaltrials.gov/study/NCT05989542 | https://clinicaltrials.gov/study/NCT04427072