Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 3
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
KRAS G12C
solid tumor basket · Combination Therapy
KRAS G12C is flagged as manual review required because public trials show inclusion required evidence in 7 contexts. FDA CDx context should be reviewed manually.
Threshold snippets
Fragmentation view
Threshold count: 7
Common snippets: KRAS G12C | KRAS G12C | KRAS G12C
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Not Found
CDx maturity score: 1/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 1
Recent signals: 1
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT02228681 | https://clinicaltrials.gov/study/NCT01188499 | https://clinicaltrials.gov/study/NCT00728390 | https://clinicaltrials.gov/study/NCT06166836 | https://clinicaltrials.gov/study/NCT07615413 | https://clinicaltrials.gov/study/NCT07209111 | https://clinicaltrials.gov/study/NCT04116541