Low Public Signal

IDH1 mutation

solid tumor basket · Therapy Not Normalized

IDH1 mutation is flagged as low public signal because public trials show resistance subgroup evidence in 3 contexts. FDA CDx context should be reviewed manually.

Role evidence

Usage summary

Strongest role: Resistance Subgroup

Inclusion-required count: 0

Treatment-assignment count: 0

Stratification count: 0

Threshold snippets

Fragmentation view

Threshold count: 0

Common snippets: None extracted

Threshold label: Low

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Not Found

CDx maturity score: 1/5

Confidence: Medium

Patent-density signal

Diagnostic appendix

Signal count: 0

Recent signals: 0

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT04762602 | https://clinicaltrials.gov/study/NCT03155620 | https://clinicaltrials.gov/study/NCT03236636