Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 6
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
HER2 / ERBB2 expression
solid tumor basket · Small Molecule Inhibitor
HER2 / ERBB2 expression is flagged as manual review required because public trials show inclusion required evidence in 9 contexts. FDA CDx context should be reviewed manually. Threshold text varies across public records.
Threshold snippets
Fragmentation view
Threshold count: 7
Common snippets: KRAS G12C | KRAS G12C | KRAS G12C
Threshold label: Fragmented
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT06126276 | https://clinicaltrials.gov/study/NCT03188965 | https://clinicaltrials.gov/study/NCT03065387 | https://clinicaltrials.gov/study/NCT03994796 | https://clinicaltrials.gov/study/NCT06804824 | https://clinicaltrials.gov/study/NCT06340568 | https://clinicaltrials.gov/study/NCT07142200 | https://clinicaltrials.gov/study/NCT02268747 | https://clinicaltrials.gov/study/NCT00551850