Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 10
Treatment-assignment count: 0
Stratification count: 0
Trial Selection Rising
HER2 / ERBB2 expression
solid tumor basket · Combination Therapy
HER2 / ERBB2 expression is flagged as trial selection rising because public trials show inclusion required evidence in 12 contexts. FDA CDx context should be reviewed manually. Threshold text varies across public records.
Threshold snippets
Fragmentation view
Threshold count: 5
Common snippets: BRAF V600E | Her2 IHC 2+ | dMMR
Threshold label: Fragmented
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: High
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT00041106 | https://clinicaltrials.gov/study/NCT00387127 | https://clinicaltrials.gov/study/NCT01325441 | https://clinicaltrials.gov/study/NCT04604132 | https://clinicaltrials.gov/study/NCT01947023 | https://clinicaltrials.gov/study/NCT02689336 | https://clinicaltrials.gov/study/NCT07608224 | https://clinicaltrials.gov/study/NCT06376136 | https://clinicaltrials.gov/study/NCT05495724 | https://clinicaltrials.gov/study/NCT05729646 | https://clinicaltrials.gov/study/NCT05272709 | https://clinicaltrials.gov/study/NCT06350006