Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 45
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
HER2 / ERBB2 expression
breast cancer · Combination Therapy
HER2 / ERBB2 expression is flagged as manual review required because public trials show inclusion required evidence in 52 contexts. FDA CDx context exists.
Threshold snippets
Fragmentation view
Threshold count: 0
Common snippets: None extracted
Threshold label: Low
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Exists
CDx maturity score: 5/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT07153965 | https://clinicaltrials.gov/study/NCT00422903 | https://clinicaltrials.gov/study/NCT02536742 | https://clinicaltrials.gov/study/NCT01151046 | https://clinicaltrials.gov/study/NCT05253053 | https://clinicaltrials.gov/study/NCT02630368 | https://clinicaltrials.gov/study/NCT00517361 | https://clinicaltrials.gov/study/NCT07544056 | https://clinicaltrials.gov/study/NCT01281150 | https://clinicaltrials.gov/study/NCT01251874 | https://clinicaltrials.gov/study/NCT03202316 | https://clinicaltrials.gov/study/NCT04975308 | https://clinicaltrials.gov/study/NCT01118975 | https://clinicaltrials.gov/study/NCT00373256 | https://clinicaltrials.gov/study/NCT07054190 | https://clinicaltrials.gov/study/NCT05631795 | https://clinicaltrials.gov/study/NCT04130152 | https://clinicaltrials.gov/study/NCT07405801 | https://clinicaltrials.gov/study/NCT02676986 | https://clinicaltrials.gov/study/NCT02955394 | https://clinicaltrials.gov/study/NCT01439282 | https://clinicaltrials.gov/study/NCT00331630 | https://clinicaltrials.gov/study/NCT02115048 | https://clinicaltrials.gov/study/NCT03505528 | https://clinicaltrials.gov/study/NCT04113863 | https://clinicaltrials.gov/study/NCT02941926 | https://clinicaltrials.gov/study/NCT05904730 | https://clinicaltrials.gov/study/NCT06857747 | https://clinicaltrials.gov/study/NCT06394661 | https://clinicaltrials.gov/study/NCT03395899 | https://clinicaltrials.gov/study/NCT03283384 | https://clinicaltrials.gov/study/NCT04872985 | https://clinicaltrials.gov/study/NCT07029399 | https://clinicaltrials.gov/study/NCT00499083 | https://clinicaltrials.gov/study/NCT03969121 | https://clinicaltrials.gov/study/NCT03128619 | https://clinicaltrials.gov/study/NCT05573126 | https://clinicaltrials.gov/study/NCT01207102 | https://clinicaltrials.gov/study/NCT01919229 | https://clinicaltrials.gov/study/NCT02007512 | https://clinicaltrials.gov/study/NCT06516289 | https://clinicaltrials.gov/study/NCT02520063 | https://clinicaltrials.gov/study/NCT05810870 | https://clinicaltrials.gov/study/NCT04293393 | https://clinicaltrials.gov/study/NCT07189884 | https://clinicaltrials.gov/study/NCT05837455 | https://clinicaltrials.gov/study/NCT05967884 | https://clinicaltrials.gov/study/NCT02511847 | https://clinicaltrials.gov/study/NCT05068141 | https://clinicaltrials.gov/study/NCT06067061 | https://clinicaltrials.gov/study/NCT07045311 | https://clinicaltrials.gov/study/NCT06889688