Role evidence
Usage summary
Strongest role: Inclusion Required
Inclusion-required count: 5
Treatment-assignment count: 0
Stratification count: 0
Manual Review Required
EGFR mutation
solid tumor basket · Immune Checkpoint Inhibitor
EGFR mutation is flagged as manual review required because public trials show inclusion required evidence in 8 contexts. FDA CDx context should be reviewed manually.
Threshold snippets
Fragmentation view
Threshold count: 2
Common snippets: MET exon 14 skipping | MSI-H
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Manual Review Required
CDx maturity score: 2/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT03371381 | https://clinicaltrials.gov/study/NCT02973997 | https://clinicaltrials.gov/study/NCT03065764 | https://clinicaltrials.gov/study/NCT03680521 | https://clinicaltrials.gov/study/NCT05063552 | https://clinicaltrials.gov/study/NCT07469774 | https://clinicaltrials.gov/study/NCT05419817 | https://clinicaltrials.gov/study/NCT05584670