Trial Selection Rising

EGFR L858R

NSCLC · Combination Therapy

EGFR L858R is flagged as trial selection rising because public trials show inclusion required evidence in 89 contexts. FDA CDx context should be reviewed manually.

Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 85

Treatment-assignment count: 0

Stratification count: 0

Threshold snippets

Fragmentation view

Threshold count: 17

Common snippets: BRAF V600E | EGFR exon 19 deletion | EGFR L858R

Threshold label: Moderate

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Not Found

CDx maturity score: 1/5

Confidence: Medium

Patent-density signal

Diagnostic appendix

Signal count: 0

Recent signals: 0

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT00550173 | https://clinicaltrials.gov/study/NCT01557959 | https://clinicaltrials.gov/study/NCT07115043 | https://clinicaltrials.gov/study/NCT05241873 | https://clinicaltrials.gov/study/NCT01351415 | https://clinicaltrials.gov/study/NCT00602030 | https://clinicaltrials.gov/study/NCT01798485 | https://clinicaltrials.gov/study/NCT06102928 | https://clinicaltrials.gov/study/NCT07314216 | https://clinicaltrials.gov/study/NCT03074864 | https://clinicaltrials.gov/study/NCT06043973 | https://clinicaltrials.gov/study/NCT04500704 | https://clinicaltrials.gov/study/NCT03399669 | https://clinicaltrials.gov/study/NCT05007938 | https://clinicaltrials.gov/study/NCT06816992 | https://clinicaltrials.gov/study/NCT07323056 | https://clinicaltrials.gov/study/NCT02036359 | https://clinicaltrials.gov/study/NCT01221077 | https://clinicaltrials.gov/study/NCT01864681 | https://clinicaltrials.gov/study/NCT06945705 | https://clinicaltrials.gov/study/NCT00577707 | https://clinicaltrials.gov/study/NCT07014202 | https://clinicaltrials.gov/study/NCT01719536 | https://clinicaltrials.gov/study/NCT06348927 | https://clinicaltrials.gov/study/NCT06668103 | https://clinicaltrials.gov/study/NCT03775486 | https://clinicaltrials.gov/study/NCT01714908 | https://clinicaltrials.gov/study/NCT00983047 | https://clinicaltrials.gov/study/NCT04636593 | https://clinicaltrials.gov/study/NCT06971406 | https://clinicaltrials.gov/study/NCT02633189 | https://clinicaltrials.gov/study/NCT07551414 | https://clinicaltrials.gov/study/NCT01859026 | https://clinicaltrials.gov/study/NCT06182761 | https://clinicaltrials.gov/study/NCT02795884 | https://clinicaltrials.gov/study/NCT05223595 | https://clinicaltrials.gov/study/NCT02098954 | https://clinicaltrials.gov/study/NCT02318368 | https://clinicaltrials.gov/study/NCT05800223 | https://clinicaltrials.gov/study/NCT01897480 | https://clinicaltrials.gov/study/NCT06334757 | https://clinicaltrials.gov/study/NCT02103257 | https://clinicaltrials.gov/study/NCT02277457 | https://clinicaltrials.gov/study/NCT04952168 | https://clinicaltrials.gov/study/NCT04552613 | https://clinicaltrials.gov/study/NCT04500717 | https://clinicaltrials.gov/study/NCT02407366 | https://clinicaltrials.gov/study/NCT05973773 | https://clinicaltrials.gov/study/NCT05334277 | https://clinicaltrials.gov/study/NCT02338011 | https://clinicaltrials.gov/study/NCT06343064 | https://clinicaltrials.gov/study/NCT05394233 | https://clinicaltrials.gov/study/NCT01580735 | https://clinicaltrials.gov/study/NCT00265317 | https://clinicaltrials.gov/study/NCT00965731 | https://clinicaltrials.gov/study/NCT05200481 | https://clinicaltrials.gov/study/NCT04459663 | https://clinicaltrials.gov/study/NCT06746870 | https://clinicaltrials.gov/study/NCT04042558 | https://clinicaltrials.gov/study/NCT06196814 | https://clinicaltrials.gov/study/NCT03164616 | https://clinicaltrials.gov/study/NCT07198841 | https://clinicaltrials.gov/study/NCT07227025 | https://clinicaltrials.gov/study/NCT06970132 | https://clinicaltrials.gov/study/NCT06749860 | https://clinicaltrials.gov/study/NCT04940637 | https://clinicaltrials.gov/study/NCT05346952 | https://clinicaltrials.gov/study/NCT03317496 | https://clinicaltrials.gov/study/NCT05568212 | https://clinicaltrials.gov/study/NCT05635708 | https://clinicaltrials.gov/study/NCT04776447 | https://clinicaltrials.gov/study/NCT03896074 | https://clinicaltrials.gov/study/NCT04832854 | https://clinicaltrials.gov/study/NCT06580665 | https://clinicaltrials.gov/study/NCT04167774 | https://clinicaltrials.gov/study/NCT05746481 | https://clinicaltrials.gov/study/NCT02888743 | https://clinicaltrials.gov/study/NCT04866017 | https://clinicaltrials.gov/study/NCT04105270 | https://clinicaltrials.gov/study/NCT06982924 | https://clinicaltrials.gov/study/NCT05651022 | https://clinicaltrials.gov/study/NCT03475953 | https://clinicaltrials.gov/study/NCT03472560 | https://clinicaltrials.gov/study/NCT03836066 | https://clinicaltrials.gov/study/NCT00762034 | https://clinicaltrials.gov/study/NCT01577654 | https://clinicaltrials.gov/study/NCT05800340 | https://clinicaltrials.gov/study/NCT03386929 | https://clinicaltrials.gov/study/NCT04323436