Manual Review Required

EGFR exon 19 deletion

NSCLC · Therapy Not Normalized

EGFR exon 19 deletion is flagged as manual review required because public trials show inclusion required evidence in 122 contexts. FDA CDx context should be reviewed manually. Threshold text varies across public records.

Role evidence

Usage summary

Strongest role: Inclusion Required

Inclusion-required count: 101

Treatment-assignment count: 0

Stratification count: 2

Threshold snippets

Fragmentation view

Threshold count: 26

Common snippets: BRAF V600E | EGFR exon 19 deletion | EGFR exon 19 deletion

Threshold label: Fragmented

FDA CDx context

Mapping summary

CDx label: Fda Cdx Context Not Found

CDx maturity score: 1/5

Confidence: Low

Patent-density signal

Diagnostic appendix

Signal count: 0

Recent signals: 0

Density label: Low

Source links

Evidence paths

https://clinicaltrials.gov/study/NCT03662477 | https://clinicaltrials.gov/study/NCT01153984 | https://clinicaltrials.gov/study/NCT05089734 | https://clinicaltrials.gov/study/NCT07291037 | https://clinicaltrials.gov/study/NCT02650375 | https://clinicaltrials.gov/study/NCT00446225 | https://clinicaltrials.gov/study/NCT00556712 | https://clinicaltrials.gov/study/NCT04250545 | https://clinicaltrials.gov/study/NCT02013206 | https://clinicaltrials.gov/study/NCT02811354 | https://clinicaltrials.gov/study/NCT07229339 | https://clinicaltrials.gov/study/NCT06758557 | https://clinicaltrials.gov/study/NCT05653752 | https://clinicaltrials.gov/study/NCT01829217 | https://clinicaltrials.gov/study/NCT03396185 | https://clinicaltrials.gov/study/NCT02404675 | https://clinicaltrials.gov/study/NCT01415011 | https://clinicaltrials.gov/study/NCT02314364 | https://clinicaltrials.gov/study/NCT01378962 | https://clinicaltrials.gov/study/NCT01858389 | https://clinicaltrials.gov/study/NCT00986284 | https://clinicaltrials.gov/study/NCT02965885 | https://clinicaltrials.gov/study/NCT01933347 | https://clinicaltrials.gov/study/NCT02744664 | https://clinicaltrials.gov/study/NCT05364073 | https://clinicaltrials.gov/study/NCT04248829 | https://clinicaltrials.gov/study/NCT02961270 | https://clinicaltrials.gov/study/NCT06864624 | https://clinicaltrials.gov/study/NCT05527808 | https://clinicaltrials.gov/study/NCT01530334 | https://clinicaltrials.gov/study/NCT03720873 | https://clinicaltrials.gov/study/NCT07554846 | https://clinicaltrials.gov/study/NCT00858403 | https://clinicaltrials.gov/study/NCT04075396 | https://clinicaltrials.gov/study/NCT01124864 | https://clinicaltrials.gov/study/NCT06382116 | https://clinicaltrials.gov/study/NCT02420405 | https://clinicaltrials.gov/study/NCT05104788 | https://clinicaltrials.gov/study/NCT06329895 | https://clinicaltrials.gov/study/NCT01121393 | https://clinicaltrials.gov/study/NCT02113813 | https://clinicaltrials.gov/study/NCT04576208 | https://clinicaltrials.gov/study/NCT00266877 | https://clinicaltrials.gov/study/NCT04619004 | https://clinicaltrials.gov/study/NCT03856697 | https://clinicaltrials.gov/study/NCT03082300 | https://clinicaltrials.gov/study/NCT03452592 | https://clinicaltrials.gov/study/NCT05519293 | https://clinicaltrials.gov/study/NCT00556322 | https://clinicaltrials.gov/study/NCT06590194 | https://clinicaltrials.gov/study/NCT03808662 | https://clinicaltrials.gov/study/NCT07268469 | https://clinicaltrials.gov/study/NCT06641609 | https://clinicaltrials.gov/study/NCT03866499 | https://clinicaltrials.gov/study/NCT01784549 | https://clinicaltrials.gov/study/NCT06563999 | https://clinicaltrials.gov/study/NCT01853826 | https://clinicaltrials.gov/study/NCT05299125 | https://clinicaltrials.gov/study/NCT05555212 | https://clinicaltrials.gov/study/NCT06221670 | https://clinicaltrials.gov/study/NCT05277701 | https://clinicaltrials.gov/study/NCT06041776 | https://clinicaltrials.gov/study/NCT06706076 | https://clinicaltrials.gov/study/NCT06987734 | https://clinicaltrials.gov/study/NCT00548093 | https://clinicaltrials.gov/study/NCT07661173 | https://clinicaltrials.gov/study/NCT03066206 | https://clinicaltrials.gov/study/NCT06685718 | https://clinicaltrials.gov/study/NCT03766490 | https://clinicaltrials.gov/study/NCT05146219 | https://clinicaltrials.gov/study/NCT01579630 | https://clinicaltrials.gov/study/NCT00567359 | https://clinicaltrials.gov/study/NCT02125240 | https://clinicaltrials.gov/study/NCT02788058 | https://clinicaltrials.gov/study/NCT01674738 | https://clinicaltrials.gov/study/NCT05257967 | https://clinicaltrials.gov/study/NCT06311981 | https://clinicaltrials.gov/study/NCT06010329 | https://clinicaltrials.gov/study/NCT06956001 | https://clinicaltrials.gov/study/NCT02186301 | https://clinicaltrials.gov/study/NCT06221475 | https://clinicaltrials.gov/study/NCT00411047 | https://clinicaltrials.gov/study/NCT01665417 | https://clinicaltrials.gov/study/NCT05967689 | https://clinicaltrials.gov/study/NCT06631989 | https://clinicaltrials.gov/study/NCT05168566 | https://clinicaltrials.gov/study/NCT04129502 | https://clinicaltrials.gov/study/NCT02183883 | https://clinicaltrials.gov/study/NCT07348965 | https://clinicaltrials.gov/study/NCT06080776 | https://clinicaltrials.gov/study/NCT01167244 | https://clinicaltrials.gov/study/NCT06315686 | https://clinicaltrials.gov/study/NCT06281964 | https://clinicaltrials.gov/study/NCT06081907 | https://clinicaltrials.gov/study/NCT03856411 | https://clinicaltrials.gov/study/NCT05361564 | https://clinicaltrials.gov/study/NCT05487391 | https://clinicaltrials.gov/study/NCT07438600 | https://clinicaltrials.gov/study/NCT00932451 | https://clinicaltrials.gov/study/NCT06955325 | https://clinicaltrials.gov/study/NCT06074588 | https://clinicaltrials.gov/study/NCT06403436 | https://clinicaltrials.gov/study/NCT02869685 | https://clinicaltrials.gov/study/NCT06865339 | https://clinicaltrials.gov/study/NCT05465733 | https://clinicaltrials.gov/study/NCT06966583 | https://clinicaltrials.gov/study/NCT05445843 | https://clinicaltrials.gov/study/NCT04059887 | https://clinicaltrials.gov/study/NCT05397093 | https://clinicaltrials.gov/study/NCT00191308 | https://clinicaltrials.gov/study/NCT05989542 | https://clinicaltrials.gov/study/NCT02864992 | https://clinicaltrials.gov/study/NCT05110196 | https://clinicaltrials.gov/study/NCT04923945 | https://clinicaltrials.gov/study/NCT04460729 | https://clinicaltrials.gov/study/NCT04427072 | https://clinicaltrials.gov/study/NCT04322578 | https://clinicaltrials.gov/study/NCT05567055 | https://clinicaltrials.gov/study/NCT02897479 | https://clinicaltrials.gov/study/NCT04992858 | https://clinicaltrials.gov/study/NCT07153770 | https://clinicaltrials.gov/study/NCT02920996