Role evidence
Usage summary
Strongest role: Treatment Assignment
Inclusion-required count: 2
Treatment-assignment count: 3
Stratification count: 0
Manual Review Required
BRAF V600E
solid tumor basket · Monoclonal Antibody
BRAF V600E is flagged as manual review required because public trials show treatment assignment evidence in 8 contexts. FDA CDx context should be reviewed manually.
Threshold snippets
Fragmentation view
Threshold count: 8
Common snippets: dMMR | BRAF V600E | MSI-H
Threshold label: Moderate
FDA CDx context
Mapping summary
CDx label: Fda Cdx Context Not Found
CDx maturity score: 1/5
Confidence: Low
Patent-density signal
Diagnostic appendix
Signal count: 0
Recent signals: 0
Density label: Low
Source links
Evidence paths
https://clinicaltrials.gov/study/NCT05097599 | https://clinicaltrials.gov/study/NCT04589845 | https://clinicaltrials.gov/study/NCT05722886 | https://clinicaltrials.gov/study/NCT05159245 | https://clinicaltrials.gov/study/NCT02693535 | https://clinicaltrials.gov/study/NCT03803553 | https://clinicaltrials.gov/study/NCT07347314 | https://clinicaltrials.gov/study/NCT04551521