Biomarker overview
BRCA1/2 mutation
Synonyms: BRCA1|BRCA2|BRCA1/2
Tumor-type contexts
Context map
| Tumor type | Drug context | Role | Strategy | Context page |
|---|---|---|---|---|
| ovarian cancer | Small Molecule Inhibitor | Inclusion Required | Low Public Signal | Open |
| solid tumor basket | Combination Therapy | Inclusion Required | Drug Development Ahead Of Cdx Context | Open |
| breast cancer | Small Molecule Inhibitor | Inclusion Required | Manual Review Required | Open |
| breast cancer | Combination Therapy | Inclusion Required | Trial Selection Rising | Open |
| ovarian cancer | Combination Therapy | Inclusion Required | Trial Selection Rising | Open |
| colorectal cancer | Small Molecule Inhibitor | Unclear | Low Public Signal | Open |
| melanoma | Immune Checkpoint Inhibitor | Resistance Subgroup | Low Public Signal | Open |
| NSCLC | Combination Therapy | Secondary Or Exploratory | Exploratory Only Signal | Open |
| solid tumor basket | Monoclonal Antibody | Inclusion Required | Drug Development Ahead Of Cdx Context | Open |
| breast cancer | Therapy Not Normalized | Inclusion Required | Manual Review Required | Open |
| solid tumor basket | Therapy Not Normalized | Inclusion Required | Low Public Signal | Open |
| NSCLC | Small Molecule Inhibitor | Stratification | Stratification Signal | Open |
| pancreatic cancer | Therapy Not Normalized | Inclusion Required | Low Public Signal | Open |
| breast cancer | Monoclonal Antibody | Mention Only | Exploratory Only Signal | Open |
| ovarian cancer | Monoclonal Antibody | Secondary Or Exploratory | Exploratory Only Signal | Open |
| ovarian cancer | Therapy Not Normalized | Inclusion Required | Low Public Signal | Open |