Program overview
Context
Indication: NSCLC
Mechanism: KRAS G12C
Modality: Small Molecule
Sponsor: Mirati Therapeutics
Registry Stop Signal
Lumicras
Lumicras is flagged as registry stop signal because public records show a registry stop signal, timeline staleness, operational burden. This is a public-data monitoring signal, not a conclusion about clinical failure, regulatory noncompliance, or sponsor intent.
Scores
Risk-signal summary
Registry: 4/5
Timeline: 4/5
Recruitment burden: 3/5
Results availability: 0/5
Program risk: 5/5
Evidence
Public links
https://clinicaltrials.gov/study/NCTCPRR001 | https://clinicaltrials.gov/study/NCTCPRR002
Linked trials
Trial-level signal details
| Trial | Status | Timeline | Results | Burden |
|---|---|---|---|---|
| NCTCPRR001 | Low Signal (RECRUITING) | stale_update_signal | primary_completion_date_past_signal | completion_date_past_signal | long_recruitment_duration_signal | Low Signal | large_enrollment_target_signal | few_sites_large_trial_signal | strict_eligibility_signal |
| NCTCPRR002 | Registry Stop Signal (SUSPENDED) | stale_update_signal | primary_completion_date_past_signal | Low Signal | strict_eligibility_signal | complex_intervention_signal |